Which NAD+ booster is best?
NAD+ has many healthy aging benefits in our bodies. Two of the main ones are that it activates genetic repair elements called sirtuins, (same as resveratrol), and it is directly involved in facilitating our energy production through the mitochondria.[1] [2] For a more comprehensive list, and a good review, see: [3]
For those who have been aware of the benefits of NAD+, which has been around since the 1990's, you will likely have encountered the raging debate of which form is the best?
Is it best to take niacin, from which NAD is derived?
Or, is taking straight NAD+ better...or its molecular partner NADH?
Or, is it best to take a precursor which converts to NAD+ in your body?
Such reasoning is common in these "which form is best?" arguments. Yet, recently it is the precursors, that your body converts to NAD+, that have taken center stage, particularly two called NR or Nicotinamide Riboside, and another called NMN (Nicotinamide Mononucleotide).
According to experts who have done the research, including David Sinclair PhD from Harvard Medical School, who wrote the book Lifespan: Why We Age and Why We Don't Have To, the one to use is NMN. There are certainly several studies that back this up. [4] As an anti-aging keener myself I am very interested in this molecule.
Recently, Natural Factors has licensed, and now offers NMN (NMNSurge 150mg), as part of its new line of Regenerlife products, with which it sets-out to address the many issues surrounding healthy aging, (inflammation, mitochondria, etc). and how to help achieve healthy ageing with functional nutrition.
I applaud this focus, largely because it is consistent with what we at Optimum Health have been saying since the early 2000's.
I encourage you to check out the new line in your quest for ever-better health, and as always, please give us your feedback on your experiences with it.
Be well!
John
References
[1] https://www.frontiersin.org/articles/10.3389/fphar.2020.01225/fu
[2] https://elifesciences.org/articles/33246
[3] https://health.selfdecode.com/blog/nad-important-increase/